Researches

Erythrocyte indexes RDW and MCW in screening iron defici›ency anemia during childhood

  • Evren Akgüneş
  • Canan Hasbal
  • Reyhan Dedeoğlu
  • Bağdagül Yavaş
  • Leyla Yolar
  • Sami Hatipoğlu

Received Date: 29.11.2006 Accepted Date: 17.03.2007 Med J Bakirkoy 2007;3(1):6-9

Objective:

Iron deficiency anemia is explained as insufficient iron take for haemoglobin production. It is the most common cause of anemia in the world. In this study we mentioned sensitivity and specifity of red cell distribution with (RDW) and mean corpuscular volume (MCV) parameters in whole blood count hence they are cheap, easy and common methods that could be used in early diagnosis of iron deficiency anemia.

Material and Methods:

A total number of 300 children between the ages of 1 month and 15 year old applied to our policlinic were included in the study. Physical examination, whole blood count, serum iron, serum iron binding capacity and serum ferittin levels were evaluated. Criteria for iron deficiency anemia were transferin saturation and ferritin cut off values according to NHANES (Second National Health and Nutrition Examination Survey).

Results:

Mean MCV values of patient group were statistically significantly lower than the control group. Mean RDW values of the patient group were statistically significantly higher than the control group.

Conclusion:

Handling RDW values of erythrocyte indexes for diagnosis of iron deficiency anemia are sensitive and specific. Combining RDW and MCV values has equal sensitivity as using RDW value alone for iron deficiency anemia.

Keywords: Anemia, iron deficiency, RDW, MCV