Research

Incidence of Atrophic Gastritis and Intestinal Metaplasia in Patients with Helicobacter Pylori Positive Duodenal Ulcer and Non-ulcer Dyspepsia

10.4274/BTDMJB.galenos.2019.20190330031302

  • Şebnem İzmir Güner
  • Murat Tuncer

Received Date: 30.03.2019 Accepted Date: 12.06.2019 Med J Bakirkoy 2019;15(3):272-279

Objective:

Helicobacter pylori was considered to be responsible for chronic atrophic gastritis and intestinal metaplasia. The frequency of coexistence of these three lesions and their relationship with H. pylori was the basis of our study.

Methods:

Therefore, data were collected to compare the incidence of atrophic gastritis and intestinal metaplasia with the same group of patients with H. pylori (+) positive duodenal ulcer and non-ulcer dyspepsia. The aim of this study was to investigate the effect of H. pylori (+) positivity on the incidence of atrophic gastritis and intestinal metaplasia. Positivity of atrophic gastritis and intestinal metaplasia was discussed in terms of statistical significance.

Results:

In our study H. pylori (+) positive group and 40-59 years of age, it was more frequent in the group of H. pylori (-) negative. There was no significant difference between the two groups in the group with positive antral gastritis between 40 and 59 years. There was no difference between the control group and the control group. Intestinal metaplasia was not detected according to the age groups.

Conclusion:

H. pylori was found to be effective on the development of duodenal ulcer, atrophic gastritis, intestinal metaplasia.

Keywords: Helicobacter pylori, duodenal ulcer, atrophic gastritis, intestinal metaplasia

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