Review

Thalassemia

  • Mehmet Kutlu
  • Hüseyin Çekmiş
  • Mesut Başak
  • Nesrin Osman
  • Özgür Açıkgöz
  • İsa Sevindir
  • Zeynep Öner Özcan

Received Date: 11.04.2006 Accepted Date: 01.05.2006 Med J Bakirkoy 2006;2(2):33-40

Thalassemia is an autosomal recessive hereditary anemia characterized by the defective or insufficient synthesis of the globin chains that make the hemoglobin molecule. We report the history, epidemiology, molecular and physiopathogenesis, clinical and laboratory findings of thalassemia which is frequent in Turkey and all around the world and recent treatment methods, prognosis and prevention of birth of babies with thalassemia.

Keywords: thalassemia, hipocromic micrositery anemia, eradication