E-ISSN: 1305-9327 ISSN: 1305-9319
8-OHdG levels in patients with allergic rhinitis
PDF
Cite
Share
Request
Researches
VOLUME: 7 ISSUE: 3
P: 104-107
September 2011

8-OHdG levels in patients with allergic rhinitis

Med J Bakirkoy 2011;7(3):104-107
DOI: 10.5350/BTDMJB201107305
Kevser Onbaşı 1
Tevfik Noyan 2
Ayşegül Çebi 3
Faruk Kıroğlu 4
1. Yüzüncü Yıl Üniversitesi Tıp Fakültesi, İç Hastalıkları AD, Van
2. Yüzüncü Yıl Üniversitesi Tıp Fakültesi, Biyokimya AD, Van
3. Yüzüncü Yıl Üniversitesi Tıp Fakültesi, Tıbbi Biyoloji Bölümü, Van
4. Yüzüncü Yıl Üniversitesi Tıp Fakültesi, Kulak-Burun Boğaz Hastalıkları AD, Van
No information available.
No information available
Received Date: 24.01.2010
Accepted Date: 27.07.2011
PDF
Cite
Share
Request

ABSTRACT

Objective:

Respiratory allergies like allergic rhinitis and allergic asthma are more frequently observed worldwide. Chronic inflammation in the respiratory tract is observed in these diseases. Oxidative stress contributes to this inflammation in the respiratory airways. 8-OHdG is a marker of oxidative stress. The aim of our study was to investigate the 8-OHdG levels in patients with respiratory allergy.

Material and Methods:

23 patients with allergy consisting of 11 men and 12 women and 23 healthy controls were enrolled to the study.

Results:

8-OHdG levels were found to be higher in allergic patients in comparison to healthy controls but it was not statistically significant.

Conclusion:

The reason for not significantly high levels of 8-OHdG levels as a marker of oxidative stress in respiratory allergy may attribute to the factor that the inflammation in respiratory allergy is less intensive in comparison to the inflammation in atopic dermatitis.

Keywords:
Allergy, 8-OHdG, allergic rhinitis, allergic asthma