ABSTRACT

Respiratory allergies like allergic rhinitis and allergic asthma are more frequently observed worldwide. Chronic inflammation in the respiratory tract is observed in these diseases. Oxidative stress contributes to this inflammation in the respiratory airways. 8-OHdG is a marker of oxidative stress. The aim of our study was to investigate the 8-OHdG levels in patients with respiratory allergy.

23 patients with allergy consisting of 11 men and 12 women and 23 healthy controls were enrolled to the study.

8-OHdG levels were found to be higher in allergic patients in comparison to healthy controls but it was not statistically significant.

The reason for not significantly high levels of 8-OHdG levels as a marker of oxidative stress in respiratory allergy may attribute to the factor that the inflammation in respiratory allergy is less intensive in comparison to the inflammation in atopic dermatitis.

Keywords: Allergy, 8-OHdG, allergic rhinitis, allergic asthma