E-ISSN: 1305-9327 ISSN: 1305-9319
Assessment of Dual-Energy X-Ray Absorptiometry (DXA) and Quantitative Computed Tomography (QCT) Methods with Biochemical Markers in Lumbar and Femoral Osteoporosis Diagnosis
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Research
VOLUME: 15 ISSUE: 1
P: 115-122
March 2019

Assessment of Dual-Energy X-Ray Absorptiometry (DXA) and Quantitative Computed Tomography (QCT) Methods with Biochemical Markers in Lumbar and Femoral Osteoporosis Diagnosis

Med J Bakirkoy 2019;15(1):115-122
DOI: 10.4274/BTDMJB.galenos.2019.20190125101336
Mualla Biçer Gençbay 1
Nilgün Işıksaçan 2
Neşe Ölmez Sarıkaya 3
1. Sağlık Bilimleri Üniversitesi Bakırköy Dr. Sadi Konuk Eğitim ve Araştırma Hastanesi, Fiziksel Tıp ve Rehabilitasyon Kliniği, İstanbul, Türkiye
2. Sağlık Bilimleri Üniversitesi Bakırköy Dr. Sadi Konuk Eğitim ve Araştırma Hastanesi, Biyokimya Kliniği, İstanbul, Türkiye
3. Sağlık Bilimleri Üniversitesi Atatürk Eğitim ve Araştırma Hastanesi, Fiziksel Tıp ve Rehabilitasyon Kliniği, Ankara, Türkiye
No information available.
No information available
Received Date: 25.01.2019
Accepted Date: 14.03.2019
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ABSTRACT

Objective:

In this study we aimed to investigate whether there is a difference in osteoporosis detection rates with dual energy x-ray absorbsiometry (DXA) and Quantitative Computed Tomography (QCT) and relationship between bone-related biochemical markers.

Methods:

34 postmenopausal women who admitted to Physical Medicine and Rehabilitation Clinic with complaints of dorsalgia. Lumbar and thoracal X-rays were obtained in all patients. Bone mineral density measurements were performed with DXA and QCT. Therefore, osteoporosis and osteopenia rates were detected. Serum levels of calcium, phosphorus, bone-spesific alkaline phosphatase (BAP), osteocalcin, parathormone, calcitonin and 25-OH vitamin D3 were measured.

Results:

The mean age of patients was 63.44+9.34 years. L2-L4 vertebrae T-score in 6/34 (17.64%) patients and Femoral neck T-score in 3/34 (8.82%) patients were <2.5 in DXA evaluation. With QCT evaluation, L2-L4 vertebrae T-score in 31/34 (91.1%) patients and femoral neck T-score in 2/34 (5.88%) patients were <2.5. Osteoporosis detection rates were higher with QCT compared to DXA and it was found statistically significant (p<0.005). Statistically significant relationship was found between lumbar and femur T scores of bone mineral density and calcitonin (p<0.005).

Conclusion:

Osteoporosis detection rates were higher with QCT compared to DXA. QCT seems to be more valuable to detect osteoporosis.

Keywords:
Dual Energy x-ray Absorbsiometry, Quantitative Computed Tomography, osteoporosis

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