Assessment of metoclopramid's postoperative analgesic efficiency during elective gynecologic operations
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Researches
P: 87-94
September 2008

Assessment of metoclopramid's postoperative analgesic efficiency during elective gynecologic operations

Med J Bakirkoy 2008;4(3):87-94
1. İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi Anesteziyoloji ve Reanimasyon Anabilim Dalı, İstanbul
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Received Date: 13.03.2008
Accepted Date: 20.07.2008
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ABSTRACT

Conclusion:

Consequently, we can conclude that metoclopramid administered in elective gynecologic operations has a postoperative analgesic efficiency.

Results:

We identified that the metoclopramid administered in elective gynecologic operations does not have any effect on the numeric rating scale values within the first 30 minutes following the extubation. Nevertheless, we observed that if a 0.5 mg/kg dose is administered immediately after the extubation, there is a significant decrease in the pethidine use within the first 24 hours after the 3rd hour.

Material and Methods:

In this double-blind study, the following random groups were formed with a total of 100 subjects. Control Group: no metoclopramid administered (n=25), Group M 0.25: 0.25 mg/kg metoclopramid administered at the end of the surgery (n=25), Group M 0.5: 0.5 mg/kg metoclopramid administered at the end of the surgery (n=25), Group M 0.5 extubation: 0.5 mg/kg metoclopramid administered after extubation (n=25).

Objective:

Opioids are the most preferred agents in pain control. Their use may cause some dose dependent undesired effects. The administration of other anesthetic agents in combination with opioids may reduce the requirement for opioids. Our purpose is to evaluate the analgesic efficiency of metoclopramid administered in combination with pethidine.

Keywords:
Surgery, postoperative pain, metoclopramid