Frequency of <i>Helicobacter Pylori</i> and Association of Location, Six Age Groups, and Assessment of Borderline of 50-year Base-age, Based on the Anatomic Pilot Region with the Degree of <i>Helicobacter Pylori</i> Colonization
PDF
Cite
Share
Request
Research
P: 381-388
December 2018

Frequency of Helicobacter Pylori and Association of Location, Six Age Groups, and Assessment of Borderline of 50-year Base-age, Based on the Anatomic Pilot Region with the Degree of Helicobacter Pylori Colonization

Med J Bakirkoy 2018;14(4):381-388
1. Giresun Üniversitesi Tıp Fakültesi, Patoloji Anabilim Dalı, Giresun, Türkiye
2. Giresun Üniversitesi Tıp Fakültesi, Genel Cerrahi Anabilim Dalı, Giresun, Türkiye
No information available.
No information available
Received Date: 27.03.2018
Accepted Date: 16.04.2018
Publish Date: 28.12.2018
PDF
Cite
Share
Request

ABSTRACT

Conclusion:

The Helicobacter pylori positivity was 55.2% in general and observed mostly in the antrum and 45-64 age group, while no any difference was detected between the location, age groups, subgroups with over and under 50 and the degree of Helicobacter pylori colonization.

Results:

The Helicobacter pylori was detected as at least one positive, 206 (55.2%) and negative, 167 (44.8%). Helicobacter pylori was positive for 73 of 147 (49.7%) in corpus and 114 of 197 (57.9%) in antrum. No difference was detected between the general stomach (p=0.292), antrum (p=0.896) and corpus (p=0.184), age groups and also new subgroup (over and under 50, in the antrum) and the Helicobacter pylori colonization.

Materials and Methods:

The histopathology results of endoscopic gastric mucosal samples of 373 cases, between February 2009 and February 2013, based on updated Sydney System had been retrospectively analysed. The existance of Helicobacter pylori had been investigated according to six age groups.

Objective:

The aim of this study is to detect the Helicobacter pylori frequency and also to evaluate the connection of the location, age groups with the degree of Helicobacter pylori colonization.

Keywords:
Helicobacter pylori, Sydney System, stomach, pyloritic antrum, gastric corpus, endoscopy, biopsy

References

1
Marshall BJ, Warren JR. Unindentified curved bacilli in the stomach of patients witch gastritis and peptic ulceration. Lancet 1984;1:1311-5.
2
Suerbaum S, Michetti P. Helicobacter pylori infection. N Engl J Med 2002;347:1175–86.
3
Oluwasola AO, Ola SO, Saliu L, Solanke TF. Helicobacter pylori infection in South Nigerians: a serological study of dyspeptic patients and healthy individuals. West Afr J Med 2002;21:138–41.
4
Schirer WH, Schoengold RJ, Baker JT, Norell JL, Jaseph CL, Okin Y, et al. Development of FlexSure HP-an immunochromatographic method to detect antibodies against Helicobacter pylori. Clin Chem 1998;44:293-8.
5
Kikuchi S, Wada O, Nakajima T, Nishi T, Kobayashi O, Konishi T, et al. Serum antiHelicobacter pylori antibody and gastric carcinoma among young adults. Cancer 1995;75:2789–93.
6
Özkan TB. Çocuklarda Helicobacter pylori enfeksiyonunda seroloji, tanı ve tedavi. Uludağ Üni Tıp Fak Derg 2007;33:81-5.
7
Mégraud F, Brassens-Rabbé MP, Denis F, Belbouri A, Hoa DQ. Seroepidemiology of Campylobacter pylori infection in various populations. J Clin Microbiol 1989;27:1870-3.
8
Go MF. Review article: natural history and epidemiology of Helicobacter pylori infection. Aliment Pharmacol Ther 2002;16:3-15.
9
Malfertheiner P1, Megraud F, O’Morain C, Bazzoli F, El-Omar E, Graham D, et al. Current concepts in management of Helicobacter pylori infection: the Maastricht III Consensus Report. Gut 2007;56:772-81.
10
Cutler AF, Havstad S, Ma CK, Blaser MJ, Perez-Perez GI, Schubert TT. Accuracy of invasive and noninvasive tests to diagnose Helicobacter pylori infection. Gastroenterology 1995;109:136–41.
11
Misiewicz JJ. The Sydney System: a new classification of gastritis. Introduction. J Gastroenterol Hepatol 1991;6:207-8.
12
Tytgat GNJ. The Sydney system: endoscopic division. Endoscopic appearances in gastritis/Duodenitis. Gastroenterol Hepatol 1991;6:223–34.
13
Rugge M, Genta RM. Staging and grading of chronic gastritis. Hum Pathol 2005;36:228-33.
14
Aydin Ö, Egilmez E, Karabacak T, Kanik A. Interobserver variation in histopathological assessment of Helicobacter pylori gastritis. World J Gastroenterol 2003;9:2232-5.
15
Price AB. The Sydney System: histological division. J Gastroenterol Hepatol 1991;6:209-22.
16
Price AB, Misiewicz JJ. Sydney classification for gastritis. Lancet 1991;337:174.
17
Dixon MF, Genta RM, Yardley JH, Correa P. Histological classification of gastritis and Helicobacter pylori infection: an agreement at last? The international Workshop on the Histopathology of gastritis. Heliccobacter 1997;2 Suppl 1:S17–S24.
18
Rugge M, Correa P, Dixon MF, Fiocca R, Hattori T, Lechago J, et al. Gastric mucosal atrophy: interobserver consistency using new criteria for classification and grading. Aliment Pharmacol Ther 2002;16:1249-59.
19
Malfertheiner P, Link A, Selgrad M. Helicobacter pylori: perspectives and time trends. Nat Rev Gastroenterol Hepatol 2014;11;628–38.
20
Atherton JC. The pathogenesis of Helicobacter pylori-induced gastro-duodenal diseases. Annu Rev Pathol 2006;1:63–96.
21
Marshall BJ, Warren JR. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet 1984;1:1311–5.
22
Pellicano R, Ribaldone DG, Fagoonee S, Astegiano M, Saracco GM, Mégraud F. A 2016 panorama of Helicobacter pylori infection: key messages for clinicans. Panminerva Med 2016;58:304–17.
23
Malfertheiner P, Chan FK, McColl KE. Peptic ulcer disease. Lancet 2009;374:1449-61.
24
Fox JG, Megraud F. Helicobacter, Murray PR, Baron EJ, Jorgensen JH, Landry ML, Pfaller MA (eds) Manual of Clinical Microbiology, 9th edn, Washington, D.C., ASM Press, 2007, s 947-962.
25
Ümit H, Ünsal G, Tezel A, Soylu AR. Helikobakter Pilori infeksiyonu ve Benign Gastroduodenal Hastalıklar, Trakya Bölgesi Verileri. Trakya Üniversitesi Tıp Fakültesi Dergisi 2010;27:400-3.
26
Salih BA, Abasiyanik MF, Bayyurt N, Sander E. H pylori infection and other risk factors associated with peptic ulcers in Turkish patients: a retrospective study. World J Gastroenterol 2007;13:3245-8.
27
Uyanıkoğlu A, Coşkun M, Binici DN, Uçar Ş, Kibar Yİ, Tay A, et al. Endoskopi yapılan hastalarda Helicobacter pylori sıklığı. Dicle Med J 2012;39:197-200.
28
Demirtas L, Sayar İ, Akbas EM, Özçiçek A, Özçiçek F, Timuroglu A, et al. Endoskopi yapılan hastalarda Helicobacter pylori sıklığı ve yerleşim yerinin yaş ve cinsiyete göre dağılımı. Dicle Tıp Derg 2014;41:507-11.
29
Esen R, Dulger AC, Begenik H, Demirtas L, Ebinc S, Aytemiz E, et al. Prevalence of Helicobacter pylori in Patients With Brucellosis. J Investig Med 2012;60:895-7.
30
Özardalı HG, Bitiren M, Nazlıgül Y, Yılmaz N. Şanlıurfa yöresinde noneroziv gastritlerde Helicobacter pylori sıklığı. Genel Tıp Derg 1998;8:149-52.
31
Demir T, Turan M, Tekin A. Kırşehir bölgesindeki dispeptik hastalarda Helicobacter pylori antijen prevalansı. Dicle Tıp Derg 2011;38:44-8.
32
Özdemir M, Baykan M. Dispeptik hastalarda H. pylori infeksiyonu tanısında H. pylori gaita antijeninin tanı değerinin incelenmesi. Genel Tıp Derg 2005;15:65-70.
33
Kalem F, Ozdemir M, Baysal B. Investigation of the presence of Helicobacter pylori by different methods in patients with dispeptic complaints. Mikrobiyol Bult 2010;44:29-34.
34
Arslan D, Tahan F, Demir F, Taşkın İ. Erciyes Üniversitesi Tıp Fakültesi Çocuk Polikliniğine başvuran sağlıklı çocuklarda Helicobacter pylori enfeksiyonunun seroprevalansı ve bunu etkileyen faktörler. Erciyes Tıp Derg 2006;28:192-6.
35
Alim A, Ataş AD, Güneş T, Ataş M, Yıldırım M, Öztekin A, Yıldızbaş H. Sivas ili merkezinde semptomatik ve asemptomatik yetişkin bireylerde Helicobacter pylori seroprevalansı. CÜ Tıp Fak Derg 2004;26:75-80.
36
Orrea P, Piazuelo MB. Natural history of Helicobacter pylori infection. Dig Liver Dis 2008;40:490-6.
37
Zhang C, Yamada N, Wu YL, Wen M, Matsuhisa T, Matsukura N. Helicobacter pylori infection, glandular atrophy and intestinal metaplasia in superfcial gastritis, gastric erosion, erosive gastritis, gastric ulcer and early cancer. World J Gastroenterol 2005;11:791-6.
38
EUROGAST Study Group. Epidemiology of and risk factors for Helicobacter pylori infection among 3194 asymptomatic subjects in 17 populations. Gut 1993;34:1672-6.
39
Goh KL, Chan WK, Shiota S, Yamaoka Y. Epidemiology of Helicobacter pylori infection and public health implications. Helicobacter 2011;16:1-9.
40
Lee I, Lee H, Kim M, Fukumoto M, Sawada S, Jakate S, et al. Ethnic difference of Helicobacter pylori gastritis: Korean and Japanese gastritis is characterized by male- and antrum-predominant acute foveolitis in comparison with American gastritis. World J Gastroenterol 2005;11:94-8.