E-ISSN: 1305-9327 ISSN: 1305-9319
Investigation of Risk Factors in Patients with Silent Posterior Cerebral Artery Infarctions
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Research
VOLUME: 14 ISSUE: 4
P: 421-426
December 2018

Investigation of Risk Factors in Patients with Silent Posterior Cerebral Artery Infarctions

Med J Bakirkoy 2018;14(4):421-426
DOI: 10.4274/BTDMJB.20180716101430
Aysel Tekeşin 1
Abdulkadir Tunç 2
Orhan Yağız 1
1. İstanbul Eğitim ve Araştırma Hastanesi, Nöroloji Kliniği, İstanbul, Türkiye
2. Sakarya Üniversitesi Eğitim ve Araştırma Hastanesi, Nöroloji Kliniği, Sakarya, Türkiye
No information available.
No information available
Received Date: 16.07.2018
Accepted Date: 26.07.2018
Publish Date: 28.12.2018
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ABSTRACT

Conclusion:

In this study, risk factors for silent posterior cerebral infarction and symptomatic cerebral infarction were found to be similar except for alcohol and gender. Determination of all these risk factors, particularly introduction of changeable, treatable risk factors, taking attention of physician and community to this subject will lead to the removal of very important distances to avoid diseases which increase mortality and morbidity such as cerebrovascular diseases.

Results:

Both groups were compared in terms of risk factors. While age, smoking, oral contraceptive and/or hormone preparation use, stroke history in family, hyperlipidemia, diabetes mellitus, heart valve disease, myocardial infarction, hypertension, transient ischemic attack history, pathologic electrocardiogram findings, heart failure and atrial fibrillation were not different in both groups, alcohol consumption and gender considered as risk factors were found to be different between the groups.

Materials and Methods:

A total of 30 patients, 23 men and 7 women, who had no previous neurological findings but who had a silent PCA infarction on cranial imaging, were included in this study. A total of 87 patients, 46 male and 41 female, who were evaluated as symptomatic cerebral infarction according to anamnesis, clinical and radiological findings and treated in our clinic during the same period, were randomized into the control group.

Objective:

Silent brain infarcts are a term used for no symptoms and findings clinically but have evidence in cranial radiologic imagings or autopsy materials. The development of cranial imaging techniques in recent years has facilitated the detection of silent brain infarcts. The aim of this study is to investigate the risk factors in patients with silent posterior cerebral artery (PCA) infarct and compare them with patients with symptomatic cerebral artery infarctions.

Keywords:
Cerebral infarction, posterior cerebral artery, risk factors

References

1
Bernick C, Kuller L, Dulberg C, Longstreth WT Jr, Monolio T, Beauchamp N, et al. Silent MRI infarcts and the risk of future stroke: the cardiovascular health study. Neurology 2001;57:1222-9.
2
Corea F, Henon H, Pasquier F, Leys D. Silent infarcts in stroke patients: patient characteristics and effect on 2-year outcome. J Neurol 2001;248:271-8.
3
Uekita K, Funayama N, Nishiura T, Makiguchi N, Sakamoto N, Aoyama H, et al. Prevalence of cervical and cerebral atherosclerosis and silent brain infarction in patients with multivessel coronary artery disease. J Cardiol 2001;38:13-20.
4
Petersen P, Madsen EB, Brun B, Pedersen F, Glydensted C, Baysen G. Silent cerebral infarction in chronic atrial fibrillation. Stroke 1987;18:1098-100.
5
Czechowsky D, Hill MD. Neurological outcome and quality of life after stroke due to vertebral artery dissection. Cerebrovasc Dis 2002;13:192-
6
Caplan LR, Tettenborn B. Vertebrobasilar occlusive disease: review of selected aspects. Posterior circulation embolism. Cerebrovasc Dis 1992;2:320-6.
7
Castaigne P, Lhermitte F, Gautier JC, Escourole R, Derouesne C, Agopıan PD, et al. Arterial occlusions in the vertebral-basilar system. Brain 1973;96:133-54.
8
Pessin MS, Lathi ES, Cohen MB, Kwan ES, Hedges TR 3rd, Caplan LR. Clinical features and mechanism of occipital infarction. Ann Neurol 1987;21:290-9.
9
Wolf PA, Belanger AJ, D’Agostino RB. Management of Risk Factors. Neurologic Clinics 1992;10:177-91.
10
Harmsen P, Tsipogianni A, Wilhelmsen L. Stroke incidence rates were unchanged, while fatality rates declined, during 1971-1987 in Göteborg, Sweden. Stroke 1992;23:1410-5.
11
Thompson DW, Furlan AJ. Clinical Epidemiology of Stroke. Neurologic Clinics 1996;14:309-15.
12
Herderschee D, Hijdra A, Algra A, Kaudstaal PJ, Kapplelle LJ, van Gijn J. Silent stroke in patients with transient ischemic attack or minor ischemic stroke. The Dutch TIA Trial Study Group. Stroke 1992;23:1220-4.
13
Shintani S, Shiigai T, Arinami T. Silent lacunar infarction on magnetic resonance imaging (MRI): risk factors. J Neurology Sci 1998;18;160:82-6.
14
Koto A. Diagnosis of silent cerebral infarction. Rinsho Shinkeigaku 1996;36:1373-5.
15
Gross CR, Kase CS, Mohr JP, Cunningham SC, Baker WE. Stroke in South Alabama: Incidence and Diagnostic Features-A Population Based Study. Stroke 1994;15:249-55.
16
Liu LH, Chia LG. The  effects  of hypertension, diabetes mellitus, atrial fibrillation, transient ischemic attack and smoking on stroke in Chinese people. Chung Hua I Hsueh Tsa Chih (Taipei) 1991;47:110-5.
17
Sarti C, Tuomilehto J,Sivenius J, Kaarsalo E, Narva EV, Salmi K, et al. Stroke Mortality and Case-Fatality Rates in Three Geographic Areas of Finland From 1983 to 1986. Stroke 1986;24:1140-7.
18
Boysen G, Nyboe J, Appleyard M, Sørensen PS, Boas J, Somnier F, et al. Stroke Incidence and risk Factors for Stroke in Copenhagen, Denmark.Stroke 1988;19:1345-53.
19
Kannel WB,Wolf PA,Verter J, McNamara PM. Epidemiologic Assessment of the Role of Blood Pressure in Stroke-The Framingham Study. JAMA 1970;214:1269-78.
20
Abbott RD,Yin Yin MA,Reed DM, et al.Risk of Stroke in Male Cigarette Smokers Cigarette Smoking and Risk of Stroke in Middle-Aged Women.The New England Journal of Medicine 1986;315:717-20.
21
Hillbom M, Haapaniemi H, Juvela S, Palomäki H, Numminen H, Kaste M. Recent Alcohol Consumption,Cigarette Smoking,and Cerebral Infarction in Young Adults. Stroke 1995;26:40-5.
22
Sacco RL. Risk Factors and Outcomes for Ischemic Stroke. Neurology 1995;45:10-4.
23
Graffagnino C, Gasecki AP,Doig GS, et al.The Importance of Family History in Cerebrovascular Disease.Stroke  1994;25 :1599-1604.
24
Iso H, Jacobs DR Jr, Wentworth D, Neaton JD, Cohen JD. Serum Cholesterol Levels and Six -Year Mortality From Stroke in 350.977 Men Screened For The Multiple Risk Factor Intervention Trial. N Engl J Med 1989;320:904-10.
25
Hachinski V, Graffagnino C, Beaudry M, Bernier G, Buck C, Donner A, et al. Lipids and Stroke. Arch Neurol 1996;53:303-8.
26
Kannel WB, McGee DL. Diabetes and Cardiovascular Disease - The Framingham Study. JAMA 1979;241:2035-8.
27
Kannel WB,Wolf PA ,Verter J.Manifestations of Coronary Disease Predisposing to Stroke-The Framingham Study.JAMA 1983;250:2942-6.
28
Sempere AP, Duarte J, Cabezas C,Claveria LE. Etiopathogenesis of transient ischemic attacks and minor ischemic strokes: A Community-based Study in Segova-Spain. Stroke 1998;29:40-5.
29
Benjamin EJ, D’agostino RB, Belanger AJ, Wolf PA, Levy D. Left Atrial Size and the Risk of Stroke and Death-The Framingham Heart Study. Circulation 1995;92:835-41.
30
Special Report From the World Health Organization Stroke -1989.Stroke 1989;20:1407-31.
31
Hunkey GJ. The effect of treating people with reversible ischemic attacks of the brain and eye on the incidence of stroke in Australia. Aust-N-Z-J-Med 1997;27:420-30.