ABSTRACT

The Plummer Vinson or Paterson-Brown-Kelly syndrome consist of an upper esophageal web, dysphagia, cheilosis, glossitis and iron deficiency anemia, usually in middle aged woman. The cause is uncertain but may be congenital or secondary to gastroesophageal reflux disease (GERD). These may occur in the proximal and distal (Schatzki’s ring) esophagus.

47 years age female patient who admitted to outpatient clinics with complaints of dysphagia, fatique, nausea, vomiting and wasting. Contrast esophagus graphy revealed a proximal esophagus stenosis. Gastroduodenoscopy could not pass distal to stenosis. The biopsy specimen obtained from the site of stenosis revealed mild, non-specific esophagitis. Computed tomography and magnetic resonance imaging of the servical and thoracic region revealed wall thickening of the esophagus proximal to stenosis and diffuse focal thickening of the anterior cervical esophagus wall neighbouring cricopharyngeus muscle seen respectively. After blood transfusion and supplemental iron therapy, patient started to swallow fluids and solid foods. At the end of 30 days of treatment dysphagia resolved completely. During long term of follow-up, patient was free of complaints.