E-ISSN: 1305-9327 ISSN: 1305-9319
Quantitative Analysis of Lead and Nickel in Benign Meningioma and Glioblastoma Multiforme
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Researches
VOLUME: 13 ISSUE: 4
P: 190-194
December 2017

Quantitative Analysis of Lead and Nickel in Benign Meningioma and Glioblastoma Multiforme

Med J Bakirkoy 2017;13(4):190-194
DOI: 10.5350/BTDMJB.20170517070728
Utku Adilay 1
Murat Gunal 2
Osman Tanriverdi 2
Ali Kemal Guler 2
Bulent Güçlü 2
Bulent Demirgil 3
1. Balikesir University, School of Medicine, Department of Neurosurgery, Balikesir
2. Bakirkoy Research and Training Hospital for Neurology, Neurosurgery and Psychiatry, Department of Neurosurgery, Istanbul
3. Kartal Dr. Lutfi Kirdar Research and Training Hospital, Department of Neurosurgery, Istanbul
No information available.
No information available
Received Date: 18.04.2017
Accepted Date: 17.05.2017
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ABSTRACT

Conclusion:

The high Nickel content of benign meningiomas compared to that of glioblastoma multiformes and the possible correlation of nickel with meningioma formation should be further evaluated. We consider that our findings carry valuable data for new researches and can contribute to worthwhile information on pathogenesis of meningioma and glioblastoma multiforme.

Results:

The level of lead in benign meningioma specimens was similar to that in glioblastoma multiforme specimens (p=0.817). The level of nickel in benign meningioma specimens were statistically higher than that in glioblastoma multiforme specimens (p=0.003).

Material and Methods:

This study was performed in pathologically diagnosed benign meningioma and glioblastoma multiforme specimens (20 specimens in each group and a total of 40 specimens) obtained from operations. Measurements of trace elements were performed with Shimadzu AA 680 atomic absorption spectrophotometer. p<0.05 was considered as statistically significant.

Objective:

The aim of this study was to compare lead (Pb) and nickel (Ni) levels in tissue samples of benign meningiomas and glioblastoma multiformes.

Keywords:
Glioblastoma multiforme, lead, meningioma, nickel