The News in Approach to the Urinary Tract Infection in Children
PDF
Cite
Share
Request
Review
P: 317-322
December 2019

The News in Approach to the Urinary Tract Infection in Children

Med J Bakirkoy 2019;15(4):317-322
1. Sağlık Bilimleri Üniversitesi, Ümraniye Eğitim ve Araştırma Hastanesi, Çocuk Kliniği, İstanbul, Türkiye
No information available.
No information available
Received Date: 10.08.2017
Accepted Date: 07.08.2019
Publish Date: 20.12.2019
PDF
Cite
Share
Request

ABSTRACT

Urinary tract infection (UTI) is one of the most common bacterial infections in childhood. All children applying with fever and diagnosed with clinical findings such as pollakiuria, dysuria, flank pain, drop by drop urination, hematuria, flammable and cloudy urine should be considered as UTI. Thus, for these children, urine cultures must be taken and a complete urinalysis examination must be performed. Ultrasonography is used to detect anatomical abnormalities in the urinary system and to determine renal parenchyma and its size. Voiding cystourethrography is used for the detection of vesicoureteral reflux. To define acute inflammation, or renal scarring renal scintigraphy with 99mTc-dimercapto succinic acid is used. Children diagnosed with UTI should be treated for 7-14 days. In case of severe clinical condition, parenteral therapy for 1-2 days, followed with oral antibiotics treatment is recommended. In the last decade there has been novel approaches to UTI in children. UTI protocols have been developed by the United Kingdom’s National Institute for Health and Care Excellence, American Academy of Pediatrics, and Italian Society of Pediatric Nephrology. In this work clinical studies, laboratory findings, screening methods, and recent developments in treatment have been reviewed for UTI in children.

Keywords: Urinary tract infection, fever, child

References

1
Morello W, la Scola C, Alberici I, Montini G. Acute pyelonephritis in children. Pediatr Nephrol 2016;31:1253-65.
2
Waddle E, Jhaveri R. Outcomes of febrile children without localising signs after pneumococcal conjugate vaccine. Arch Dis Child 2009;94:144-7.
3
Jackson EC. Urinary tract infections in children: knowledge updates and a salute to the future. Pediatr Rev 2015;36:153-64.
4
Hellström A, Hanson E, Hansson S, Hjälmås K, Jodal U. Association between urinary symptoms at 7 years old and previous urinary tract infection. Arch Dis Child 1991;66:232-4.
5
Marild S, Jodal U. Incidence rate of first-time symptomatic urinary tract infection in children under 6 years of age. Acta Paediatr 1998;87:549-52.
6
Lambert H, Coulthard M. The child with urinary tract infection. Clinical Paediatric Nephrology Webb NJA, Postlethwaite RJ, eds. third ed. Oxford University Press 2003:197-225.
7
National Institute for Health and Clinical Excellence. Urinary tract infection in children: diagnosis, treatment and longterm management. 2007. (http://www.nice .org.uk/nicemedia/pdf/CG54fullguideline .pdf.)
8
Subcommittee on Urinary Tract Infection, Steering Committee on Quality Improvement and Management, Roberts KB. Urinary tract infection: clinical practice guideline for the diagnosis and management of the initial UTI in febrile infants and children 2 to 24 months. Pediatrics 2011;128:595-610.
9
Ammenti A, Cataldi L, Chimenz R, Fanos V, La Manna A, Marra G, et al; Italian Society of Pediatric Nephrology. Febril Urinary Tract Infections in young children. Recommendations for the diagnosis, treatment and follow -up. Acta Paediatr 2012;101:451-7.
10
Buonsenso D, Cataldi L. Urinary tract infections in children: a review. Minerva Pediatr 2012;64:145-57.
11
Hansson S, Jodal U. Urinary tract infection. In: Avner ED, Harmon WE, Niaudet P, eds. Pediatric nephrology. 5th ed. Philadelphia: Lippincott Williams & Wilkins, 2004:1007-26.
12
Fisher DJ. Pediatric urinary tract infection. http://emedicine.medscape.com/ article/969643-overview. Accessed March 16, 2016.
13
Tullus K, Jacobson SH, Katouli M, Brauner A. Relative importance of eight virulence characteristics of pyelonephritogenic Escherichia coli strains assessed by multivariate statistical analysis. J Urol 1991;146:1153-5.
14
Jantunen ME, Siitonen A, Ala-Houhala M, Ashorn P, Föhr A, Koskimies O, et al. Predictive factors associated with significant urinary tract abnormalities in infants with pyelonephritis. Pediatr Infect Dis J 2001;20:597-601.
15
Whiting P, Westwood M, Bojke L, Palmer S, Richardson G, Cooper J, et al. Clinical effectiveness and cost-effectiveness of tests for the diagnosis and investigation of urinary tract infection in children: a systematic review and economic model. Health Technol Assess 2006;10:1-154.
16
UTI Guideline Team. Cincinnati Children’s Hospital Medical Center: evidence-based care guideline for medical management of first urinary tract infection in children 12 years of age or less. Guideline 7, pages 1–23, November, 2006. Available at: http:// www.cincinnatichildrens.org/svc/dept-div/health-policy/evbased/ uti.htm. (accessed March 14, 2011).
17
Hoberman A, Wald ER, Penchansky L, Reynolds EA, Young S. Enhanced urinalysis as a screening test for urinary tract infection. Pediatrics 1993;91:1196-99.
18
Pecile P, Romanello C. Procalcitonin and pyelonephritis in children. Curr Opin Infect Dis 2007;20:83-7.
19
Huang HP, Lai YC, Tsai IJ, Chen SY, Tsau YK. Renal ultrasonography should be done routinely in children with first urinary tract infections. Urology 2008;71:439-43.
20
Hoberman A, Charron M, Hickey RW, Baskin M, Kearney DH, Wald ER. Imaging studies after a first febrile urinary tract infection in young children. N Engl J Med 2003;348:195-202.
21
Lee MD, Lin CC, Huang FY, Tsai TC, Huang CT, Tsai JD. Screening young children with a first febrile urinary tract infection for high-grade vesicoureteral reflux with renal ultrasound scanning and technetium-99m-labeled dimercaptosuccinic acid scanning. J Pediatr 2009;154:797-802.
22
Lee HY, Soh BH, Hong CH, Kim MJ, Han SW. The efficacy of ultrasound and dimercaptosuccinic acid scan in predicting vesicoureteral reflux in children below the age of 2 years with their first febrile urinary tract infection. Pediatr Nephrol 2009; 24:2009-13.
23
Lebowitz RL, Olbing H, Parkkulainen KV, Smellie JM, Tamminen- Mobius TE. International system of radiographic grading of vesicoureteric reflux. International Reflux Study in Children. Pediatr Radiol 1985;15:105-9.
24
Coulthard MG. Vesicoureteric reflux is not a benign condition. Pediatr Nephrol 2009;24:227-32.
25
Doganis D, Siafas K, Mavrikou M, Issaris G, Martirosova A, Perperidis G, et al. Does early treatment of urinary tract infection prevent renal damage? Pediatrics 2007;120:e922-8.
26
Hewitt IK, Zucchetta P, Rigon L, Maschio F, Molinari PP, Tomasi L, et al. Early treatment of acute pyelonephritis in children fails to reduce renal scarring: data from the Italian Renal Infection Study Trials. Pediatrics 2008;122:486-90.
27
Hoberman A, Wald ER, Hickey RW, Baskin M, Charron M, Majd M, et al. Oral versus Initial intravenous therapy for urinary tract infections in young febrile children. Pediatrics 1999;104:79-86.
28
Montini G, Toffolo A, Zucchetta P, Dall’Amico R, Gobber D, Calderan A, et al. Antibiotic treatment for pyelonephritis in children: multicentre randomized controlled non-inferiority trial. BMJ 2007;335:86.
29
Hewitt IK, Pennesi M, Morello W, Ronfani L, Montini G. Antibiotic Prophylaxis for Urinary Tract Infection-Related Renal Scarring: A Systematic Review. Pediatrics 2017;139. pii: e20163145.
30
Hacımustafaoğlu M. Çocuklarda üriner sistem enfeksiyonları. J Pediatr Sci 2011;7:68-75.
31
Guay DR. Cranberry and urinary tract infections. Drugs 2009;69:775-807.
32
Ferrara P, Romaniello L, Vitelli O, Gatto A, Serva M, Cataldi L. Cranberry juice for the prevention of recurrent urinary tract infections: a randomized controlled trial in children. Scand J Urol Nephrol 2009;43:1-5.
33
Lavigne JP, Vitrac X, Bernard L, Bruyère F, Sotto A. Propolis can potentialise the anti-adhesion activity of proanthocyanidins on uropathogenic Escherichia coli in the prevention of recurrent urinary tract infections. BMC Res Notes 2011;4:522.
2024 ©️ Galenos Publishing House