ABSTRACT

In this study we searched the efficiency of prosthetic mesh materials used in the repairment of the large abdominal wall defects.

We used Wistar-Albino type rat with a mean weight of 250 gr. Three groups were created with equal numbers of rats (n: 10). The abdominal wall of the rats in the first group were cut by midline incision and sutured by 3/0 vicyrl, skin was closed with 3/0 silk in a continuous manner. In the second group; abdominal wall of the rats were cut in 3 cm length, 2 cm width. Then abdominal wall was sutured by 3/0 vicryl tightly, skin was closed with 3/0 silk in a continuous manner. In the third group the abdominal defect is the same as the second group and the abdominal wall defect was repaired by prolen mesh, which was sutured by 3/0 vicryl. Blood samples were drawn from arteria femoralis for blood gases analysis, urea and creatinin levels.

In the terms of vena cava inferior pressure; there is significant difference between first and second groups, but there is not a significant difference between the first and the third group. Second group is significantly different from the first and the third group; third group is significantly different from the second group and there is no difference between the first and the third group.

As a result we detected that in the cases which fascial edges can not be proximated, closing the fascia by using mesh instead of closing tensely prevents intrabdominal hypertension.

Keywords: Experimental study, intraabdominal hypertension, mesh